Studies supporting the connection between cholesterol levels, oxidation of cholesterol, and coronary heart disease.
Oxidized Phospholipids, Lp(a) Lipoprotein, and Coronary Artery Disease
- Concludes that circulating levels of oxidized LDL are strongly associated with coronary artery disease, particularly in patients 60 years of age or younger.
Endothelial Dysfunction, Oxidative Stress, and Risk of Cardiovascular Events in Patients With Coronary Artery Disease
- Finds the stress of vascular oxydation contributes to dysfunction in coronary cell walls and predicts the risk of cardiovascular events in patients with coronary artery disease.
Molecular link between cholesterol, cytokines and atherosclerosis
- Finds that the presence of cholesterol and its oxydated derivative result in accumulation and formation of atherosclerotic plaque.
The effect of cholesterol lowering on carotid and femoral artery wall stiffness and thickness in patients with familial hypercholesterolaemia
- Finds that one year of cholesterol lowering therapy in familial hypercholesterolaemia (high cholesterol) decreases the wall stiffness in the common femoral artery and the arterial wall thickness in the common carotid artery.
Purple grape juice improves endothelial function and reduces the susceptibility of LDL cholesterol to oxidation in patients with coronary artery disease.
- Finds ingestion of purple grape juice reduces LDL susceptibility to oxidation in coronary artery disease patients.
Association of small low-density lipoprotein particles with the incidence of coronary artery disease in men and women
- Finds that the ratio of total cholesterol to HDL cholesterol is a strong independent predictor of coronary artery disease. Also supports the role for small, dense LDL particles in the the cause of atherosclerosis.
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